Table 9 Alleles reclassified as "unassigned".
From: HLA class I supertypes: a revised and updated classification
Allele | Previous assignment | B pocket match | F pocket match | Comments |
|---|---|---|---|---|
A*0102 | A01 | - | A01 full | Single difference with A*0101 (F to S) at position 9 in B pocket is non-conservative. |
A*2404 | A24 | A24 full | - | F pocket key sequence is similar to A02 and B27 (hydrophobic), so A24 is still likely. |
A*3401 | A03 | - | A03 full | N/K in 63/66 are relatively unique, otherwise similar to A03 in the B pocket. |
A*4301 | A01 | - | A01 full | Q to N in 63 is only difference with A*2601, so A01 is still likely. |
B*1301 | B62 | B62 key | - | Unusual F pocket. |
B*1302 | B62 | B62 key | - | Unusual F pocket. |
B*1506 | B62 | - | B07 B27 B44 B62 full | Single conservative change (Y to F) at position 99 of B pocket, comapred to B*1501; B62 still likely. |
B*1521 | B62 | - | B07 B62 full | S to C change in position 67 is the onlyB pocket difference with B*1501, so B62 is still likely. |
B*2708 | B27 | B27 full | - | Position 77 T to N change is only difference with b*2704, so B27 is still likely. |
B*3802 | B27 | B27 full | - | I to T in position 80 of the F pocket is the only difference with B*3801, so B27 is still likely. |
B*4701 | B44 | - | B27 key | Y to F at position 99 is the only difference with B*4402-3 in the B pocket, so B44 is still likely. |
B*4901 | B44 | B44 full | - | F full pocket is similar to B*3801 (hydrophobic), so B44 is still likely. |