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Figure 5 | BMC Immunology

Figure 5

From: The Retinoic Acid Receptor-α mediates human T-cell activation and Th2 cytokine and chemokine production

Figure 5

A RAR-α agonist specifically inhibits Th1-associated cytokine production by anti-CD3,-activated PBMC. IFN-γ (panel A) and IL-12p70 (panel B) proteins were quantitated by ELISA in supernatants of 48 h, anti-CD3,-activated PBMC treated with control EtOH, ATRA (10-7 M), AM580 (10-7 M), or an RAR- α antagonist, RO 41–5254 (10-7 M). The values shown represent the average obtained from 4 donors ± SEM. Means that express different superscripts are significantly different by at least p < 0.03.

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BMC Immunology

ISSN: 1471-2172

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