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Figure 4 | BMC Immunology

Figure 4

From: Divergence of canonical danger signals: The genome-level expression patterns of human mononuclear cells subjected to heat shock or lipopolysaccharide

Figure 4

Merge of two top scoring IPA networks derived from the list of 1,476 upregulated heat shock-responsive genes. The merged network is depicted in the context of cellular compartments. This upregulated heat shock-responsive network contains two nodes having a high degree of connectivity to other network genes: interleukin-1β (IL1B) located in the extracellular compartment and jun oncogene (JUN) located in the nuclear compartment. Gold lines indicate connectivity between the two merged networks. See text for network derivation, and see Additional file 5 for network gene list and Additional file 4 for network legend.

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