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Figure 6 | BMC Immunology

Figure 6

From: Divergence of canonical danger signals: The genome-level expression patterns of human mononuclear cells subjected to heat shock or lipopolysaccharide

Figure 6

Merge of two top scoring IPA networks derived from the list of 1,445 downregulated heat shock-responsive genes. The merged network is depicted in the context of cellular compartments. This downregulated heat shock-responsive network contains two nodes in the nuclear compartment having a high degree of connectivity to other network genes: v-myc myelocytomatosis viral oncogene homolog (MYC) and Sp1 transcription factor (SP1). Gold lines indicate connectivity between the two merged networks. See text for network derivation, and see Additional file 7 for network gene list and Additional file 4 for network legend.

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