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Table 1 Functional annotations associated with the upregulated LPS- and heat shock-responsive genes, respectively.

From: Divergence of canonical danger signals: The genome-level expression patterns of human mononuclear cells subjected to heat shock or lipopolysaccharide

  LPS Heat Shock
Pathway (p value) • Apoptosis signaling (1.5E-10) • Apoptosis signaling (1.8E-3)
  • Inflammation mediated by chemokine and cytokine signaling (2.1E-7) • Angiogenesis (3.2E-2)
  • Toll receptor signaling (9.6E-6)  
  • Integrin signaling (1.4E-2)  
Biological process (p value) • Immunity and defense (2.2E-25) • Protein folding (2.1E-14)
  • Signal transduction (5.8E-23) • Protein metabolism and modification (1.7E-10)
  • Intracellular signaling cascade (3.0E-16) • Stress response (1.8E-10)
  • Cell surface receptor mediated signaling (2.7E-10) • Protein phophorylation (1.7E-6)
  • Cytokine and chemokine mediated signaling (3.1E-10) • Immunity and defense (2.0E-5)
Molecular function (p value) • Signaling molecule (1.4E-10) • Chaperone (1.2E-16)
  • Other transcription factor (3.0E-7) • Hsp 70 family chaperone (1.9E-7)
  • Chemokine (3.3E-6) • Protein kinase (2.8E-6)
  • Cytokine receptor (1.2E-5) • Transcription factor (2.0E-4)
  • Select regulatory molecule (8.9E-5) • Chaperonin (1.2E-3)
  1. Data are based on the PANTHER database using the default parameters in the database and Bonferroni correction for multiple comparisons.