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Table 5 Top 10 functional annotations for two merged networks downregulated in response to LPS (based on p value).

From: Divergence of canonical danger signals: The genome-level expression patterns of human mononuclear cells subjected to heat shock or lipopolysaccharide

Category Term # of genes p-value
SP_PIR_KEYWORDS aminoacyl-tRNA synthatase 6 1.7E-4
SP_PIR_KEYWORDS protein biosynthesis 8 5.2E-4
GOTERM_BP_ALL sterol metabolism 7 6.0E-4
GOTERM_BP_ALL cellular physiological process 57 7.0E-4
GOTERM_BP_ALL biosynthesis 21 1.0E-3
GOTERM_MF_ALL aminoacyl-tRNA ligase activity 6 1.3E-3
GOTERM_MF_ALL ligase activity, carbon-oxygen bonds 6 1.3E-3
GOTERM_BP_ALL amino acid activation 6 1.6E-3
GOTERM_BP_ALL tRNA aminoacylation for protein translation 6 1.6E-3
GOTERM_BP_ALL tRNA amioacylation 6 1.6E-3
  1. The analysis is based on the default parameters in D.A.V.I.D. and uses Benjamini-Hochberg correction for multiple testing.