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Table 7 Top 10 functional annotations for two merged networks commonly upregulated in response to both LPS and heat shock (based on p value).

From: Divergence of canonical danger signals: The genome-level expression patterns of human mononuclear cells subjected to heat shock or lipopolysaccharide

Category Term # of genes p-value
GOTERM_BP_ALL inflammatory response 12 2.9E-8
GOTERM_BP_ALL response to wounding 14 4.6E-8
GOTERM_BP_ALL response to external stimulus 14 8.2E-7
INTERPRO_NAME small chemokine, interleukin-8-like 6 2.7E-4
GOTERM_MF_ALL protein binding 29 1.5E-4
GOTERM_MF_ALL chemokine activity 6 8.2E-5
GOTERM_MF_ALL chemokine receptor binding 6 8.2E-5
GOTERM_BP_ALL response to stress 16 9.3E-5
SMART_NAME SCY1 6 1.2E-4
SP_PIR_KEYWORDS chemotaxis 6 3.2E-4
  1. The analysis is based on the default parameters in D.A.V.I.D. and uses Benjamini-Hochberg correction for multiple testing. 1Intercrine alpha family (small chemokine C-X-C) (chemokine CXC)