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Table 7 Top 10 functional annotations for two merged networks commonly upregulated in response to both LPS and heat shock (based on p value).

From: Divergence of canonical danger signals: The genome-level expression patterns of human mononuclear cells subjected to heat shock or lipopolysaccharide

Category

Term

# of genes

p-value

GOTERM_BP_ALL

inflammatory response

12

2.9E-8

GOTERM_BP_ALL

response to wounding

14

4.6E-8

GOTERM_BP_ALL

response to external stimulus

14

8.2E-7

INTERPRO_NAME

small chemokine, interleukin-8-like

6

2.7E-4

GOTERM_MF_ALL

protein binding

29

1.5E-4

GOTERM_MF_ALL

chemokine activity

6

8.2E-5

GOTERM_MF_ALL

chemokine receptor binding

6

8.2E-5

GOTERM_BP_ALL

response to stress

16

9.3E-5

SMART_NAME

SCY1

6

1.2E-4

SP_PIR_KEYWORDS

chemotaxis

6

3.2E-4

  1. The analysis is based on the default parameters in D.A.V.I.D. and uses Benjamini-Hochberg correction for multiple testing. 1Intercrine alpha family (small chemokine C-X-C) (chemokine CXC)