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Figure 2 | BMC Immunology

Figure 2

From: CXCL10+ T cells and NK cells assist in the recruitment and activation of CXCR3+ and CXCL11+ leukocytes during Mycobacteria-enhanced colitis

Figure 2

Change in SAA levels in IBD patients and in IL-10-/- mice after mycobacterial challenge. Sera from 62 CD and 88 UC female patients and 32 normal healthy female donors, not undergoing any treatment, were isolated and evaluated for the presence of SAA. IL-10-/- mice on B6 background, received 200 μl of cream milk alone (; control) or cream milk containing 104 CFU of live () or heat-killed (▲) M. avium paratuberculosis. SAA levels during Mycobacteria-enhanced colitis as well as IBD patients and healthy donors were measured by ELISA. Experimental groups consisted of 5 mice, and experiments were repeated 3 times. The data presented are the mean ± SEM concentration of SAA. Asterisks indicate statistically significant differences, i.e., p < 0.01, between control and Mycobacteria-treated groups or healthy donors and IBD patients.

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