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Figure 4 | BMC Immunology

Figure 4

From: CpG oligodeoxynucleotide stimulates production of anti-neutrophil cytoplasmic antibodies in ANCA associated vasculitis

Figure 4

CpG-B also induced the production of relevant IgG autoantibodies in patients with other autoimmune diseases. PBMCs from 4 patients with autoimmune thyroiditis and 3 patients with anti-phospholipid antibody syndrome were cultured with CpG-B and IL-2. Each patient assay was paired with a healthy control. After 12 days of culture, supernatants from autoimmune thyroiditis patients were tested by ELISA for IgG anti-thyroperoxidase (TPO) as shown in A. Supernatants from anti-phospholipid antibody syndrome patients were tested for IgG anti-cardiolipin antibodies (ACLA) as shown in B.

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BMC Immunology

ISSN: 1471-2172

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