Figure 1
From: Leukotriene B4-loaded microspheres: a new therapeutic strategy to modulate cell activation
LTB 4 -loaded MS provoke leukocyte infiltration in the lung parenchyma. The lungs were removed on day 7 after the administrations, fixed and paraffin-embedded, followed by staining with HE. Lung sections are representative of three experiments with 5-LO-/- mice (5 animals each group) that received (A) PBS; (B) LTB4 in solution (3 × 10-8 M); (C) unloaded MS and (D) LTB4-loaded MS (5 × 10-7 M or 160 ng/ml). Magnifications of each section: ×50 and ×400.