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Table 4 Differences in mRNA expression of CRS and cryptdins in small intestine of different mouse strains

From: Regional variations in Paneth cell antimicrobial peptide expression along the mouse intestinal tract

 

C57BL/6, N = 2

NMRI/KI, N = 4

C3H/HeN, N = 4

CRS1C

2.0 × 106

7.5 × 105

1.1 × 106

CRS4C

Not present

3.0 × 107

1.4 × 106

Crypt1

4.4 × 106

5.6 × 106

6.9 × 106

Crypt4

Not present

2.3 × 105

1.9 × 105

Crypt4 C57BL/6

5.8 × 106

Not present

Not present

  1. Average mRNA levels in whole small intestine of adult C57BL/6, NMRI/KI and C3H/HeN mice measured by qRT-PCR. N = number of mice. Numbers denotes mRNA copy numbers per 10 ng RNA. Note that C57BL/6 mice lack CRS4C-1 to 3 and cryptdin 4 and display a unique cryptdin 4 variant.