Liposome type | Mean Diameter | Zeta Potential |
|---|
| | nm ± SD(i)(%)(ii) | mV ± SD(iii) |
|---|
Entrapping DNA-hsp65
| 244.53 ± 64.05 (93.21) 985.92 ± 229.12 (6.79) | 32.8 ± 4.0 |
Complexing DNA-hsp65
| 616.73 ± 152.35 (93.4) 2749.56 ± 774.90 (7.53) | 27.3 ± 2.3 |
Empty
| 247.47 ± 86.26 (93.96) 862.92 ± 140.78 (6.04) | 26.9 ± 2.4 |
- (i) Mean ± standard deviation (SD). Liposome composition- EPC:DOTAP:DOPE 50:25:25 molar. Liposomes containing DNA-hsp65 at molar charge ratio 1:10 (cationic lipid:DNA). Diameter measurements were done in independent samples: n = 8 for liposomes complexed with DNA-hsp65 and n = 9 for liposomes entrapping DNA-hsp65 and empty liposomes.
- (ii) Percentages refer to distribution number-weighted of particles.
- (iii) Mean ± standard deviation (SD). Zeta potential measurements in three independent samples (n = 3)
