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Figure 4 | BMC Immunology

Figure 4

From: The frequency of CD127low expressing CD4+CD25high T regulatory cells is inversely correlated with human T lymphotrophic virus type-1 (HTLV-1) proviral load in HTLV-1-infection and HTLV-1-associated myelopathy/tropical spastic paraparesis

Figure 4

Correlation between HTLV-1 proviral load of HTLV (Green triangle), and HAM/TSP (Red circle) with expression of CD127 or CTLA-4 in CD25+ or CD25high CD4+ T cells subsets. HTLV-I proviral load is expressed in copies per 1,000 cells. There was no correlation with CD4+CD25+ T cells (A). No correlation with CD4+CD25high T cells (B). Inverse correlation with the percentage of CD4+CD25+CTLA-4+ T cells in HTLV only; r = -0.7500, p = 0.0255 (C). No correlation with CD4+CD25highCTLA-4+ T cells (D). Lack of correlation with the percentage of CD4+CD25+CD127low T cells (E). (F) Negative correlation with CD4+CD25highCD127low T cells in HTLV (r = -0.7333, p = 0.03) and HAM/TSP (r = -0.8108, p = 0.034).

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