TY - JOUR AU - Guest, Christopher B. AU - Chakour, Kenneth S. AU - Freund, Gregory G. PY - 2008 DA - 2008/07/30 TI - Macropinocytosis is decreased in diabetic mouse macrophages and is regulated by AMPK JO - BMC Immunology SP - 42 VL - 9 IS - 1 AB - Macrophages (MΦs) utilize macropinocytosis to integrate immune and metabolic signals in order to initiate an effective immune response. Diabetes is characterized by metabolic abnormalities and altered immune function. Here we examine the influence of diabetes on macropinocytosis in primary mouse macrophages and in an in vitro diabetes model. SN - 1471-2172 UR - https://doi.org/10.1186/1471-2172-9-42 DO - 10.1186/1471-2172-9-42 ID - Guest2008 ER -