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Figure 5 | BMC Immunology

Figure 5

From: Functional imaging of interleukin 1 beta expression in inflammatory process using bioluminescence imaging in transgenic mice

Figure 5

hIL-1βP-driven luciferase expression in IL-1β-luc transgenic mice in an oxazolone-CHS model. (A) Female cHS4I-hIL-1βP-Luc mice (n = 3) are sensitized with oxazolone on day -6. On day 0, the right ears were challenged with oxazolone and the left ears were treated with vehicle. Imaging analysis was performed on day – 6, 0, 1, and 30. (B) Quantification of luciferase expression (photons/sec) in all the ears with LivingImage software. Data were presented as mean ± SE. (C) Ear thickness was measured on day – 6, 0, 1, and 30 with a micrometer. Data represent mean ± SE. *** indicate significant differences at p < 0.001. p/s/cm2/sr: photons/sec/cm2/steradian.

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