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Figure 1 | BMC Immunology

Figure 1

From: Secretion of celiac disease autoantibodies after in vitro gliadin challenge is dependent on small-bowel mucosal transglutaminase 2-specific IgA deposits

Figure 1

Small-bowel mucosal transglutaminase 2 (TG2, red)-specific IgA deposits (green) after 24 hours' organ culture. A) Positive staining (arrow) in the mucosal villous of a short-term treated celiac disease patient (gluten-free diet for three years). B) Negative IgA deposits (arrow) in the small-bowel mucosa of long-term treated celiac disease patient (gluten-free diet for eight years). Co-localization of IgA deposits with TG2 is shown in yellow. Magnification 40×.

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