Table 2 Prediction performance of selected representative servers in order to correctly predict the majority (95%) of binders
From: Evaluation of MHC class I peptide binding prediction servers: Applications for vaccine research
Server | Thr2 | TP (binding) | TN (binding) | FP (binding) | FN (binding) | TP (tumor epitopes) | TP (viral epitopes) |
|---|---|---|---|---|---|---|---|
BIMAS (A) | 0.003 | 31 | 105 | 38 | 2 | 84 (99%) | 44 (100%) |
MHCP_I (A) | 1,000 | 31 | 7 | 136 | 2 | 80 (94%) | 40 (91%) |
IEDB_SMM (B) | 79,000 | 31 | 109 | 34 | 2 | 85 (100%) | 44 (100%) |
NHP_CP (C) | 0 | 31 | 126 | 17 | 2 | 79 (93%) | 40 (91%) |
IEDB_ANN (D) | 39,000 | 31 | 75 | 68 | 2 | 85(100%) | 42 (95%) |
MULTI_SVM (D) | 3.9 | 31 | 101 | 42 | 2 | 84 (99%) | 44 (100%) |
NETM_ANN (D) | 40,000 | 31 | 113 | 30 | 2 | 85 (100%) | 44 (100%) |