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Table 3 Prediction performance of selected representative servers in order to exclude all false positives

From: Evaluation of MHC class I peptide binding prediction servers: Applications for vaccine research

Server

Thr3

TP (binding)

TN (binding)

FP (binding)

FN (binding)

TP (tumor epitopes)

TP (viral epitopes)

BIMAS (A)

2

10

143

0

23

76 (89%)

39 (89%)

MHCP_I (A)

10

0

143

0

33

2 (2%)

1 (2%)

IEDB_SMM (B)

1,000

10

143

0

23

77 (91%)

38 (86%)

NHP_CP (C)

0.5

6

143

0

27

76 (89%)

40 (91%)

IEDB_ANN (D)

10,000

9

143

0

24

76 (89%)

39 (89%)

MULTI_SVM (D)

5.8

4

143

0

29

75 (88%)

40 (91%)

NETM_ANN (D)

10,000

15

143

0

18

80 (94%)

41 (93%)