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Table 3 Patients with IgG subclass deficiency

From: Primary immunodeficiency in infection-prone children in southern Sweden: occurrence, clinical characteristics and immunological findings

Deficiencya

No. of patients

Treatment

IgG1

0

-

IgG2

23

Ig infusion: 5 patients

IgG3

4

-

IgG4 b

0

-

IgG1 + IgG2

1

Ig infusion

IgG1 + IgG3

0

-

IgG2+ IgG3

1

Ig infusion

IgG2 + IgA

3

Ig infusion: 1 patient

IgG3 + low IgA, IgM

1

Ig infusion

  1. aDefined as a significant decrease in serum concentration of one or more subclasses of IgG when total IgG concentration is normal (6). Values below age-matched reference intervals were considered as significantly decreased.
  2. bAge >12 years.