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Table 2 Patient characteristics at assay

From: An increase of CD83+ dendritic cells ex vivo correlates with increased regulatory T cells in patients with active eosinophilic granulomatosis and polyangiitis

 

Relapsen = 12

Remissionn = 14

P

Duration from onset of EGPA (months)

61.3 ± 100.7

75.1 ± 96.4

NS*

BVAS at relapse or remission

14.5 ± 9.5

0 ± 0

< 0.01*

Prednisolone dose at relapse or remission

10.4 ± 4.6

9.6 ± 7.6

NS*

Immunosuppressant use at relapse or remission (%)

75

35.7

<0.05

CYC/AZA/CSA/MTX/RTX

7/1/1/0/0

3/2/0/0/0

NS

No. of eosinophils in peripheral blood

350.8 ± 262.0

309.3 ± 273.2

NS*

FOXP3+ cells among CD4+ T cells (%)

0.5 ± 0.4

5.8 ± 2.1

< 0.01

IL-10+ cells among CD4+CD25+ T cells (%)

0.3 ± 0.8

10.9 ± 11.4

< 0.01

TGF-β+ among CD4+CD25+ T cells (%)

0.2 ± 0.7

7.4 ± 6.1

< 0.01

IL-2+ among CD4+CD25 T cells (%)

9.9 ± 14.1

32.2 ± 25.3

< 0.05

  1. BVAS, Birmingham Vasculitis Activity Score; AZA, azathioprine; CSA, cyclosporin A; CYC, cyclophosphamide; MTX, methotrexate; RTX, rituximab; NS, not significant.
  2. A P value of <0.05 was considered to be statistically significant.
  3. *Two-way ANOVA using repeated-measures algorithm.
  4. Mann–Whitney U-test.
  5. Chi-squared testing revealed no significant differences between the frequencies of the characteristics measured in the two groups.