Figure 6From: Effects of the mTOR inhibitor Rapamycin on Monocyte-Secreted ChemokinesSP600125 and PD98059 suppressed LPS-induced MIP-1α (a) and MIP-1β (c) expression. BAY 11–7085 suppressed both LPS-induced MCP-1α and MCP-1β expression (b, d). These results suggested that the p38, JNK-MAPKs, and NF-κB pathways were critical to LPS-induced MDC expression by monocytes.Back to article page