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Table 1 Bacterial clearance

From: C-Jun N-terminal kinase (JNK) isoforms play differing roles in otitis media

Time after NTHi inoculation

WT # of culture positive plates

WT Quadrants positive in culture positive plates

JNK1-/-# of culture positive plates

JNK1-/-Quadrants positive in culture positive plates

JNK2-/-# of culture positive plates

JNK2-/-Quadrants positive in culture positive plates

Day 1

4/6

4.00

5/6

3.20

3/6

2.33

Day 2

6/6

3.00

2/6

3.00

4/6

2.75

Day 3

3/6

1.00

4/6

2.50

5/6

2.80

Day 5

0/6

0.00

4/6

2.00

2/6

1.50

Day 10

0/6

0.00

3/6

1.00

1/6

4.00

Day 14

0/6

0.00

2/6

1.00

1/6

1.00

Day 21

0/6

0.00

0/6

0.00

2/6

2.50

  1. No NTHi colonies were isolated from the ME for WT mice, from 5 days after infection onward. In JNK1-/- mice, NTHi were isolated up to day 14. In JNK2-/- mice, NTHi was isolated throughout the 21 day observation period.