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Figure 3 | BMC Immunology

Figure 3

From: GM-CSF-loaded chitosan hydrogel as an immunoadjuvant enhances antigen-specific immune responses with reduced toxicity

Figure 3

OVA-specific immune responses in mice immunized with various adjuvants with or without GM-CSF. Sera were collected from adjuvant-immunized mice (5 per group) 2 weeks after the last immunization and were used to characterize OVA-specific antibodies. Mice received an immunization with 50 μg of OVA and 50 ng of GM-CSF via subcutaneous injection. Seven days after immunization, experimental groups were boosted. (A) Titers of OVA-specific IgG in mice immunized with various adjuvants. (B) Titers of OVA-specific IgG1 in mice immunized with various adjuvants. (C) Titers of OVA-specific IgG2a in mice immunized with various adjuvants. The data are presented as means±S.D. (n = 5), (*p <0.01).

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BMC Immunology

ISSN: 1471-2172

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