Table 4 AUC of the ROC for the discrimination between an infection and non-infectious inflammation and between bacterial and viral infection
From: The discriminative capacity of soluble Toll-like receptor (sTLR)2 and sTLR4 in inflammatory diseases
Biomarker | Infection vs no infection | P-value | Bacterial infection vs viral infection | P-value |
|---|---|---|---|---|
AUC (95% CI) | Â | AUC (95% CI) | ||
CRP | 0.74 (0.69-0.80) | - | 0.94 (0.90-0.96) | - |
sTLR2 | 0.60 (0.54-0.66) | 0.0004 | 0.58 (0.51-0.64) | <0.0001 |
sTLR4 | 0.72 (0.66-0.79) | 0.80 | 0.75 (0.70-0.80) | <0.0001 |
sTLR2 + sTLR4 | 0.65 (0.60-0.70) | 0.01 | 0.75 (0.69-0.80) | <0.0001 |
sTLR2 + CRP | 0.75 (0.70-0.80) | 0.66 | 0.94 (0.90-0.96) | 0.36 |
sTLR4 + CRP | 0.76 (0.71-0.80) | 0.25 | 0.95 (0.91-0.97) | 0.13 |