Figure 4

Comparison of Safranin-O/Fast-Green staining of mouse articular cartilage surface of hind joints, showing the proteoglycan stained by Safranin-O (red) in cartilage matrix in a 16 week old DBA/1^−/−mouse (A,B) and a congenic DBA.B-1^−/−mouse (C,D). Arrow indicates the decreased Safranin-O staining in articular cartilage in congenic DBA.B-1^−/− mouse joint (C,D), as compared to that observed in a DBA/1^−/− mouse (A,B).