Table 3 Disease associated genes in different categories and pathways
Rheumatoid arthritis | Systemic lupus erythematosus | Immune thrombocytopenic purpura | Guillain-barre syndrome | |
|---|---|---|---|---|
Number of Genes Associated >> | 667 | 448 | 49 | 73 |
v Categories v | ||||
Antigen Processing & Presentation | 6.30% | 9.15% | 14.29% | 8.22% |
Antimicrobials | 19.64% | 17.19% | 28.57% | 39.73% |
BCR Signaling Pathway | 2.85% | 2.23% | 6.12% | 4.11% |
Cytokines + Receptors | 28.49% | 18.97% | 30.61% | 24.66% |
> Chemokines + Receptors | 7.05% | 3.79% | 4.08% | 5.48% |
> Interferons + Receptors | 0.30% | 0.67% | 4.08% | 4.11% |
> Interleukins + Receptors | 5.55% | 4.02% | 8.16% | 5.48% |
> TGF-b Family Members + Receptors | 1.20% | 0.45% | 2.04% | 2.74% |
> TNF Family Members + Receptors | 3.00% | 2.90% | 4.08% | 1.37% |
Natural Killer Cell Cytotoxicity | 6.45% | 6.47% | 12.24% | 9.59% |
TCR Signaling Pathway | 4.50% | 4.46% | 10.20% | 10.96% |
Other Immune-Related | 28.94% | 29.46% | 34.69% | 19.18% |
Immune Disease Pathways | 19.34% | 31.47% | 38.78% | 28.77% |
Infectious Disease Pathways | 28.79% | 29.46% | 34.69% | 45.21% |
Unclassified | 16.49% | 19.20% | 8.16% | 17.81% |