miRNA expression is altered in colon, blood, and saliva from Crohn’s disease and ulcerative colitis subjects. Total RNA from NL, CD, and UC colon biopsies was pooled and used for TaqMan qRT-PCR analysis for the indicated miRNAs. miRNA expression was normalized to U6 expression. Statistical significance was calculated using the Student’s t-test relative to the healthy NL control. At least 23 distinct specimens were included in each pooled group of colon biopsies. 30 and 5 distinct specimens were included in each pooled group of blood and saliva samples, respectively.