Figure 5
From: IL-17 and IL-23 in lupus nephritis - association to histopathology and response to treatment
Immunostaining of IL-17 in renal tissue. The figure demonstrates a kidney biopsy from a patient with lupus nephritis WHO class V. Representative micrographs displaying (A) an inflammatory infiltrate with T cells as demonstrated by a positive CD3-staining and in (B) the same infiltrate from a consecutive section stained with irrelevant isotype control antibody. In (C), IL-17 staining is demonstrated, predominantly found in the inflammatory infiltrate shown in A, and (D) demonstrates staining with the corresponding isotype control antibody. Original magnifications: 12.5×.