Table 2 Baseline levels of cytokines in patients at baseline vs. controls, and baseline vs. follow-up levels in patients
From: IL-17 and IL-23 in lupus nephritis - association to histopathology and response to treatment
Patients, baseline median (range) | Patients, follow-up median (range) | Controls median (range) | p | |
|---|---|---|---|---|
IL-6, pg/ml | 10.02 (0.62-81.78) | 2.18 (0.62-4.64) | <0.001 | |
3.29 (0.62-30.72) | <0.001 | |||
IL-10, pg/ml | 9.78 (0.54-81.04) | 0.54 (0.54-3.90) | <0.001 | |
4.95 (0.54-37.21) | <0.002 | |||
TNF-α, pg/ml | 1.24 (0.55-12.51) | 0.55 (0.55-4.29) | 0.10 | |
1.00 (0.55-78.22) | 0.27 | |||
IFN-γ, pg/ml | 7.05 (0.52-338.9) | 0.52 (0.52-8.97) | 0.03 | |
6.63 (0.52-278.2) | 0.75 | |||
IL-17, pg/ml | 97.42 (3.30-381.6) | 3.30 (3.30-62.66) | <0.001 | |
47.98 (3.30-824.5) | 0.01 | |||
IL-23, pg/ml | 5.52 (0.66-121.5) | 0.66 (0.66-0.66) | <0.001 | |
3.27 (0.66-32.67) | 0.06 | |||
TGF-β, ng/ml | 42.99 (10.22-85.94) | 82.71 (57.80-119.1) | <0.001 | |
49.46 (25.04-121.7) | 0.005 |