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Table 3 Association between combinations of cytokine gene polymorphisms and susceptibility to LTBI and PTB

From: Association between cytokine gene polymorphisms and tuberculosis in a Chinese population in Shanghai: a case–control study

  INF-γ TNF-a IL-10 IL-2 HC LTBI PTB LTBI.vs.Health PTB.vs.LTBI
874 −308 −1082 −330 OR(95%CI) OR(95%CI)
1 A A A G 56 30 12 1.07(0.657-1.734) 0.79(0361–1.624)
2 A A A T 113 47 43 0.81(0.555-1.178) 2.01(1.252-3.219)*
3 A A G T 50 41 5 1.70(1.079-2.665)* 0.23(0.069-0.588)
4 A G A G 70 32 22 9.25(5.300-15.932)* 1.41(1.062-2.575)*
5 A G A T 105 67 46 1.32(0.936-1.855) 1.46(0.994-2.248)
6 A G G G 29 28 7 1.98(1.125-3.505)* 0.48(0.176-1.159)
7 A G G T 44 26 11 1.19(0.695-2.009) 0.84(0.367-1.795)
8 T A A G 29 20 9 2.47(1.300-4.599)* 0.89(0.353-2.101)
9 T A A T 64 32 11 1.00(0.623-1.578) 0.67(0.300-1.400)
10 T A G G 35 11 7 0.62(0.281-1.263) 0.33(0.107-1.945)
11 T A G T 71 30 8 0.83(0.518-1.319) 0.52(0.202-1.179)
12 T G A G 24 19 9 1.61(0.823-3.093) 0.95(0.371-2.236)
13 T G A T 85 43 17 1.01(0.673-1.508) 0.77(0.405-1.425)
14 T G G G 38 20 6 1.05(0.574-1.884) 0.59(0.191-1.550)
15 T G G T 124 28 16 0.42(0.263-0.645) 1.15(0.570-2.259)
  1. Notes: HC, healthy controls; LTBI, subjects with latent tuberculosis infection; PTB, patients with pulmonary tuberculosis; INF-γ, interferon γ; TNF-α, tumor necrosis factor α; IL-10, interleukin 10; IL-2, interleukin 2.
  2. *p < 0.05.