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Table 2 Effect of cathinone and crude khat extract on hematological parameters (mean ± SEM) of mice (n = 6)

From: Evaluation of immunomodulatory activities of methanolic extract of khat (Catha edulis, Forsk) and cathinone in Swiss albino mice

Dose (mg/kg) RBC*106/μL HB (g/dL) HCT (%) MCV (FL) MCH (pg) MCHC (g/dL) Platelet*10 3 /μL
Cathinone        
Control 8.07 ± 0.3 12.82 ± 0.47 44.3 ± 0.67 54.85 ± 0.03 15.76 ± 0.047 30.91 ± 0.13 884 ± 26
0.625 7.68 ± 0.15 12.51 ± 0.27 40.6 ± 0.14 52.82 ± 0.46 16.28 ± 0.042 30.82 ± 0.2 694 ± 16*
1.25 8.72 ± 0.15 13.7 ± 0.23 43.5 ± 0.78 52.2 ± 0.00 15.63 ± 0.067 30.1 ± 0.0 628 ± 12*
2.5 8.92 ± 0.64 12.1 ± 1.04 40.7 ± 0.23 51.4 ± 0.11** 15.25 ± 0.086 29.65 ± 0.2* 581 ± 23*
5 8.07 ± 0.31 12.12 ± 0.04 44.2 ± 0.67 51.8 ± 0.03** 15.55 ± 0.047 28.7 ± 0.13* 509 ± 48*
Khat        
50 8.3 ± 0.72 12.7 ± 1.11 43.3 ± 1.06 52.06 ± 1.5 15.67 ± 0.31 29.52 ± 0.53 670 ± 12.7
100 8.7 ± 0.25 13.6 ± 0.45 46.1 ± 1.94 52.9 ± 1.36 15.23 ± 0.02 29.42 ± 0.25 639 ± 27.6*
200 8.63 ± 0.37 12.66 ± 0.25 43 ± 1.71 51.66 ± 1.4* 15.63 ± 0.07 29.53 ± 0.15 543 ± 42*
  1. NB: Values with asterisk are significantly different: * = P < 0.05, ** = P < 0.01 (ANOVA, Tukey’s HSD post-hoc test) from values of control.