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Table 3 Delay type hypersensitivity responses (Mean ± SEM) in mice (n = 6) treated with crude khat extract and cathinone

From: Evaluation of immunomodulatory activities of methanolic extract of khat (Catha edulis, Forsk) and cathinone in Swiss albino mice

Substance Dose (mg/Kg) DTH response (mm) mean paw edema
Cathinone Control 4.75 ± 0.857
Positive control (Dexamethason) 0.04 ± 0.02
0.625 mg/kg 4.71 ± 0.57
1.25 mg/kg 5.1 ± 0.51
2.5 mg/kg 6.06 ± 0.37*
5 mg/kg 6.56 ± 0.97**
Khat 50 mg/kg 8.06 ± 0.91**
100 mg/kg 7.26 ± 1.17**
200 mg/kg 3.2 ± 0.775*
  1. NB: Values with asterisk are significantly different (ANOVA, Tukey’s HSD post-hoc test) from values of control: * = P < 0.01, ** = P < 0.001.