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Figure 1 | BMC Immunology

Figure 1

From: C-reactive protein enhances activation of coagulation system and inflammatory response through dissociating into monomeric form in antineutrophil cytoplasmic antibody-associated vasculitis

Figure 1

CD62p expression of platelets in static incubation system. A: Flow cytometry analysis of the effect of pCRP and mCRP on the CD62p expression of platelets incubated statically with ANCA-induced netting neutrophils. ADP at a concentration of 100 μmol/L was used as a positive control. Results are expressed as the percentages of CD62p positive platelets. Four tubes of each group were analyzed and averaged. B-G: Representative images of the flow cytometry analysis of the percentages of platelets expressing CD62p. B: PRP were incubated with ANCA-induced netting neutrophils alone. C: PRP were incubated with ANCA-induced netting neutrophils pretreated with DNase I (0.1 U/μL). D: PRP were incubated with pCRP (60 μg/mL) alone. E: PRP were incubated with mCRP (60 μg/mL) alone. F: PRP were incubated with ANCA-induced netting neutrophils and mCRP (60 μg/mL). G: PRP were incubated with ANCA-induced netting neutrophils, mCRP (60 μg/mL) and DNase I (0.1 U/μL).

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BMC Immunology

ISSN: 1471-2172

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