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Figure 5 | BMC Immunology

Figure 5

From: C-reactive protein enhances activation of coagulation system and inflammatory response through dissociating into monomeric form in antineutrophil cytoplasmic antibody-associated vasculitis

Figure 5

Influence of the mCRP deposited during perfusion experiments on platelets activation. A: Representative images of activated platelets (CD62p positive) after immobilized ANCA-induced netting neutrophils were perfused with pCRP-containing PRP or mCRP-containing PRP. The concentration of pCRP or mCRP was 60 μg/mL. Activated platelets were visualized using FITC conjugated anti-CD62P mAb (green). Scale bar: 50 μm. B: Calculated levels of the deposited CD62p positive platelets after immobilized ANCA-induced netting neutrophils were perfused with PRP which did not contain pCRP or mCRP, with pCRP-containing PRP or with mCRP-containing PRP. Results were expressed as activated platelets/visual field. Five visual fields of each group were analyzed.

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