Figure 4

Histology assessment of allogeneic grafts. At 2wks after transplantation, no inflammatory infiltrates and graft edema were found in all groups. At 4wks, obvious inflammatory infiltration in the graft stroma and graft edema as well was visible in control solution-treated recipients. A smaller amount of inflammatory infiltration could be found in the TGF-β-treated recipients. However, neither grafts with mixed treatment of ATRA and TGF-β nor syngeneic grafts presented inflammatory infiltration and graft edema. At 8wks, more or less inflammatory cells were infiltrated in the graft treated with ATRA, TGF-β and control solution. In contrast, the lamellar structure of stromal collagen was clearly visible in grafts with a mixed treatment, despite epithelium proliferation. (Hematoxylin - eosin staining, × 200).