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Table 1 B. pertussis proteins spotted on the peptide microarray slides

From: Serum reactome induced by Bordetella pertussis infection and Pertussis vaccines: qualitative differences in serum antibody recognition patterns revealed by peptide microarray analysis

 

Protein ID

Accession nu

Function

Vaccine component

1

Pertussis toxin subunit 1 precursor, (ptxA)

O69258

Toxin subunit

All vaccines

2

Pertussis toxin subunit 2 precursor, (ptxB)

P04978

Toxin subunit

 

3

Pertussis toxin subunit 3 precursor, (ptxC)

P04979

Toxin subunit

 

4

Pertussis toxin subunit 4 precursor, (ptxD)

P0A3R5

Toxin subunit

 

5

Pertussis toxin subunit 5 precursor, (ptxE)

P04981

Toxin subunit

 

6

P.69 protein (pertactin/PRN)

CAA09473

Adhesin

DTPa5 & DTPwc

7

Filamentous hemagglutinin (FHA)

AAA22974

Adhesin

DTPA2,5 & DTPwc

8

Fim2 pilic subunit (Fim2)

Q8VVA0

Adhesin

DTPa5

9

Fim3 pilic subunit (Fim3) precursor

CAA35920/P17835

Adhesin

DTPa5& DTPwc

10

Tracheal colonization factor (TCF)

CAA08832/O86135

Adhesin

DTPwc

11

Bifunctional hemolysin-adenylate cyclase precursor (ATC/cyaA)

P15318

toxin

DTPwc

12

Outer membrane porin protein precursor (OMP)

CAA41398, 1/Q04064

Outer membrane porin protein

DTPwc

13

Outer membrane porin protein (OmpQ)

CAD12825, Q8VV98

Outer membrane porin protein

DTPwc

14

GTP-binding elongation factor (BipA)

Q7VYR0

Regulatory protein

DTPwc

15

Bordetella resistance to killing (BrkA)

AAA51646

Putative adhesion

DTPwc

16

Vag8 protein (autotransporter) (Vag8)

CAD12828/Q8VV95

Autotransporter

DTPwc

17

Putative autotransporter (BapC)

AAC31207

Autotransporter

DTPwc

  1. B. pertussis proteins spotted on the peptide microarray slides used in the study. The list includes all the acellular vaccines components and other Bp virulence factors. DTPwc: Diphtheria Tetanus Pertussis whole cell vaccine; DTPa5: Diphtheria Tetanus Pertussis 5 component vaccine; DTPa2: Diphtheria Tetanus Pertussis 2 component vaccine.