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Table 2 Recognition frequency of target peptides spotted on the microarray slides, stratified per study group and by target proteins

From: Serum reactome induced by Bordetella pertussis infection and Pertussis vaccines: qualitative differences in serum antibody recognition patterns revealed by peptide microarray analysis

B. pertussis protein

GENE

Whooping cough

DTP wc

DTPa5

DPTa2

DT

Pertussis toxin subunit 1 precursor

PtxS1

4

   

1

Pertussis toxin subunit 2 precursor

PtxS2

3

 

1

 

1

Pertussis toxin subunit 3 precursor

PtxS3

5

2

2

 

2

Pertussis toxin subunit 4 precursor

PtxS4

2

1

2

 

1

Pertussis toxin subunit 5 precursor

PtxS5

3

4

2

 

2

P.69A protein (pertactin)

Prn

11

3

6

2

4

Filamentous hemagglutinin

fhaB

27

10

11

5

14

Fim2 pilic subunit

fim2

1

1

   

Serotype 3 fimbrial subunit precursor

fim3

2

    

Tracheal colonization factor

tcfA

19

15

10

7

9

Bifunctional hemolysin-adenylate cyclaseprecursor

cyaA

61

41

50

22

39

Outer membrane porin protein precursor

ompP

27

16

16

4

12

Outer membrane porin protein OmpQ

ompQ

37

32

36

12

24

GTP-binding elongation factor

bipA

26

16

13

9

8

Bordetella resistance to killing

brkA

10

7

8

9

6

Vag8 protein (Autotransporter)

vag8

44

28

28

8

18

Putative autotransporter

bapC

69

47

54

21

25

  1. The table shows the recognition frequency of target peptides spotted on the microarray slides, stratified per study group and by target proteins. Whooping cough: children who received the placebo and developed whooping cough; DTPwc: Diphtheria Tetanus Pertussis whole cell vaccine; DTPa5: Diphtheria Tetanus Pertussis 5 component vaccine; DTPa2: Diphtheria Tetanus Pertussis 2 component vaccine; DT: children who received only the Diphtheria Tetanus vaccine; all groups N = 10; none of the children in the vaccine groups, including DT, were diagnosed with a condition related to B. pertussis infection.