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Table 2 Elevated inflammation biomarkers but similar microbial translocation in older HIV-infected subjects

From: Increased inflammation but similar physical composition and function in older-aged, HIV-1 infected subjects

 

Uninfected n = 10

HIV n = 21

P value*

LPS EU/ml

0.37 (0.30/0.44)

0.34 (0.26/0.42)

0.638

sCD14 ng/ml

1154 (993/1315)

1892 (1716/2069)

≤0.001

OPN ng/ml

38.9 (32.8/44.9)

45.7 (37.4/54.0)

0.257

sICAM-1 ng/ml

631 (510/766)

1086 (815/136)

0.022

sVCAM-1 ng/ml

49.0 (34.5/63.6)

71.4 (61.6/81.2)

0.009

CRP ng/ml

650 (369/931)

4582 (2675/6488)

≤0.001

IL-6 pg/ml

0.42 (0.08/0.92)

2.10 (1.19/3.01)

0.003

D-dimer ng/ml

104.5 (4.2/204.8)

229.1 (72.6/385.6)

0.417

  1. All values are means (5/95 % CI). *Mann–Whitney U-test. The underlined values are statistically significant at P < 0.006 (adjusted for multiple comparisons); the Italicized values show a trend toward statistical significance at P < 0.05
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BMC Immunology

ISSN: 1471-2172

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