Fig. 3

Transcription factors suppressed by IAV within 6 h post-infection. a BETA was used to identify transcription factor matrices with significantly different activity within 6 h following IAV infection (triangles) compared to NDV infection (squares) (q < 0.1). Only TFs that are also differentially-expressed at the mRNA level are shown. b ISGF3 activity (y-axis) was calculated by BETA using the V$ISRE_01 matrix following IAV infection (triangles) and NDV infection (squares). The grey area indicates the 95 % confidence interval for activity, with the dashed line representing the absence of transcriptional activity