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Fig. 5 | BMC Immunology

Fig. 5

From: Impairment of dendritic cell function and induction of CD4+CD25+Foxp3+ T cells by excretory-secretory products: a potential mechanism of immune evasion adopted by Echinococcus granulosus

Fig. 5

ES induced CD4+CD25+ Foxp3+ T cell generation. BMDC–T cell co-culture was performed as described above in the presence of 50 nM OVA. After initial incubation, T cells were reactivated with plate-immobilized anti-mouse CD3 for 12 h, harvested and analyzed by combined surface and intracellular FACS staining. T cells were gated on the basis of CD4+ staining and analyzed for surface CD25 staining and intracellular Foxp3 staining. The percentage of CD4+CD25+Foxp3+ T cells is indicated in the upper right quadrant

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