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Fig. 2 | BMC Immunology

Fig. 2

From: IFNγ+ Treg in-vivo and in-vitro represent both activated nTreg and peripherally induced aTreg and remain phenotypically stable in-vitro after removal of the stimulus

Fig. 2

Absolute counts of different CD4+CD25+Foxp3+CD127- Treg subsets in the blood of 12 healthy controls. Two-thirds of all CD4+CD25+Foxp3+CD127- Treg were Helios+IFNγ- nTreg, only a small minority represents Helios+IFNγ+ activated nTreg or Helios-IFNγ+ peripherally induced aTreg. The additionally investigated parameters give insight into the immunosuppressive armamentarium and the mechanisms of IFNγ+ Treg function. Data are given as mean ± SEM

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BMC Immunology

ISSN: 1471-2172

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