Fig. 2

β-Catenin expression regulates the differentiation of effector iNKT2 and iNKT17 cells. a-b Frequency and total iNKT cell numbers from control and β-CAT-cKO mice (a) and from control and β-CAT-Tg mice (b) (n ≥ 4, mean ± sem). Numbers over dot plots refer to total thymocyte cell numbers. c-d Representative dot plots showing iNKT1, iNKT2 and iNKT17 populations among iNKT cells (top) and total numbers (bottom) from control and β-CAT-cKO mice (c) and from control and β-CAT-Tg mice (d). Gating strategies are shown in right (n ≥ 3, mean ± sem). * P < .05; ** P < .01; *** P < .001