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Fig. 2 | BMC Immunology

Fig. 2

From: Immunogenicity of twenty peptides representing epitopes of the hepatitis B core and surface antigens by IFN-γ response in chronic and resolved HBV

Fig. 2

ELISPOT results of chronic HLA-A2 patients. a Stimulation index (SI) for CHB patients divided in two groups: Patients with the HLA-A2 genotype and patients without HLA-A2 genotype. Each datapoint represents the mean response to each individual epitope. The patients without HLA-A2 genotype had a significantly higher amount of IFN-γ production. If we included RHB patients in the analysis, the results were still significant. Unpaired two-tailed t-test with equal SD, N = 15 in each group, **** indicates p < 0.0001, ** indicates p = 0.0099. b AUC showed that difference in response profiles did reach statistical significance when comparing SFC x MSS area, Kruskal-Wallis (Dunn’s) multiple comparisons test, *** indicates p = 0.0009. c Spot number correlated with spot size. No significant correlation was found

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BMC Immunology

ISSN: 1471-2172

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