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Fig. 3 | BMC Immunology

Fig. 3

From: Immunogenicity of twenty peptides representing epitopes of the hepatitis B core and surface antigens by IFN-γ response in chronic and resolved HBV

Fig. 3

ELISPOT results of HLA-A11 and non-HLA-A11 patients. a Stimulation index (SI) for patients divided in 5 groups. Each datapoint represents the mean response to each individual epitope. CHB patients with HLA-A11 had significantly higher SI of MSS compared to all other group. No significance were found when analysis spot forming cells; R: resolved; C: chronic. Unpaired one-way ANOVA, Kruskal-Wallis (Dunn’s) multiple comparison test, Non HLA-A11 (R) (N = 8), HLA-A11 (R) (N = 2), HLA-A2 (C) (N = 15), Other HLA (C) (N = 10), **** indicates p < 0.0001, top line: 95 % CI of difference (−2.8;-1.9), middle line: 95 % CI (−2.7;-1.8), bottom line: 95 % CI (−2.4;-1.6), **: 95 % CI (1.1;1.9). b AUC showed that difference in response profiles did reach statistical significance when comparing SFC x MSS area, Kruskal-Wallis (Dunn’s) multiple comparisons test, **** indicates p < 0.0001

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