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Fig. 4 | BMC Immunology

Fig. 4

From: Dendritic cell immunoreceptor 1 alters neutrophil responses in the development of experimental colitis

Fig. 4

Decreased numbers of MPO+ neutrophils in Dcir1 −/− mice colitic colon. a The descending colons from WT and Dcir1 −/− mice that were untreated or treated with DSS for 5 days were stained with FITC-anti-Ly6G (green), anti-MPO (red) and APC-anti-CD11b (blue). Cell nuclei were visualized using DAPI (white). Arrowheads represent cells stained with triple colors. ME: muscle externa, S: submucosa, M: mucosa. Each area is delineated by a white dotted line. Magnification × 10. Scale bars represent 100 μm. b Numbers of MPO+ neutrophils (CD11b+Ly6G+) were counted in vertical sections of colon from WT and Dcir1 −/− mice treated as in (a) Data are the combined results of two independent experiments (n = 3-5). *P < 0.05. Data are expressed as the mean ± SEM

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