| Controls | HIV+ | ||
---|---|---|---|---|
 | N = 10 | N = 43 | ||
 | Median or n | IQR or % | Median or n | IQR or % |
Demography and lifestyle | Â | Â | Â | Â |
 Age (years) | 48.1 | 41.9–62.3 | 49.8 | 43.3–55.2 |
 Smoking | 0 | 0 % | 14* | 32.6 % |
Body composition | Â | Â | Â | Â |
 Lipodystrophy | — | — | 14 | 32.6 % |
 BMI (kg/m2) | 25.4 | 24.7–28.6 | 25.1 | 23.0–27.7 |
 FMI (kg/m2) | 5.2 | 4.6–7.5 | 4.6 | 3.4–6.4 |
 VAT (cm2) | 111.6 | 93.5–157.5 | 150.8 | 115.0–212.2 |
  lLMI (kg/m2) | 6.4 | 6.2–6.8 | 6.1 | 5.7–6.6 |
Metabolic parameters | Â | Â | Â | Â |
 HOMA-IR | 0.5 | 0.5–1.3 | 1.2* | 0.6–2.4 |
 Metabolic syndrome | 1 | 10 % | 20 | 46.5 % |
Biomarkers of inflammation | Â | Â | Â | Â |
 IL-6 (pg/mL) | 1.1 | 0.7–2.4 | 1.6 | 1.1–2.6 |
 suPAR (ng/mL) | 1.8 | 1.5–2.1 | 2.2* | 1.8–2.8 |
HIV- and immune-related parameters | Â | Â | Â | Â |
 HIV duration (years) | — | — | 14 | 6.6–21.0 |
 ART duration (years) | — | — | 10.2 | 4.4–14.8 |
 Current PI treatment | — | — | 13 | 30.2 % |
 Current NRTI treatment | — | — | 43 | 100 % |
 Current NNRTI treatment | — | — | 28 | 65.1 % |
 Other current ART | — | — | 4 | 9.30 % |
 HIV RNA ≤20 copies/mL | — | — | 39 | 90.7 % |
 CD4+ T cell count (cells/μL) | 729 | 674–880 | 580 | 403–820 |
 CD8+ T cell count (cells/μL) | 373 | 281–440 | 828*** | 618–1120 |
 CD4:CD8 ratio | 2.0 | 1.8–3.0 | 0.7*** | 0.5–1.0 |