Fig. 4

Correlations between eosinophils count (per microliter) in the colonic submucosa and eosinophil count in the peripheral blood (a) or the basement membrane-to-crypt distance (b) in patients with eosinophilic granulomatosis with polyangiitis (EGPA). The basement membrane-to-crypt distance reflected edema in the colonic submucosa. Closed circles: mucous membrane of colon biopsied at the onset of EGPA. Open circles: mucous membrane of colon biopsied in remission after treatment with corticosteroids with or without immunosuppressants. Correlation coefficients (r values) and P values were calculated by using Spearman’s rank correlation test