Fig. 6
From: Dectin-2-dependent host defense in mice infected with serotype 3 Streptococcus pneumoniae
Reduced production of serotype-specific Ab against pneumococcal capsular polysaccharides in Dectin2KO mice. Anti-PPS3 IgG (a), IgG3 (b) and IgM (c) concentrations in BALF before infection or 24 h post-infection were measured as OD450 values at × 1, ×3 and × 9 dilution, respectively. Each group consists of six to seven mice. Similar results were obtained in three independent experiments. *, p < 0.05, compared with Dectin-2KO mice 24 h post-infection. Open circles, WT mice 24 h post-infection; closed circles, Dectin-2KO mice 24 h after infection; open triangles, WT mice before infection; closed triangles, Dectin-2KO mice before infection