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Table 2 Select biological categories significantly associated with differentially regulated genes

From: The effects of storage temperature on PBMC gene expression

Pathway Tool

Database

Pathway

Enrichment P-value

Cluster

Number of genes (% of Genes)

IPA

Canonical Pathways

Toll-like Receptor Signaling

4.70E-09

1

12 (16.7 %)

2

7 (9.7 %)

DAVID

GO-BP

Cell Death

5.80E-08

1

46 (10.6 %)

2

34 (9.4 %)

DAVID

GO-BP

Regulation of Transcription

9.90E-08

1

141 (32.3 %)

2

70 (19.4 %)

IPA

Canonical Pathways

NFkB Signaling

1.20E-06

1

17 (10.1 %)

2

9 (5.3 %)

DAVID

GO-BP

Defense Response

1.50E-05

1

36 (8.2 %)

2

27 (7.5 %)

DAVID

KEGG

MAPK Signaling Pathway

7.4E-04

1

27 (14.2 %)

2

7 (5.0 %)

  1. This table summarizes the number genes associated with the common pathways identified by IPA and DAVID that were either in cluster 1 or 2