Table 4 Fifteen most up regulated genes in isolated microglia from SIV-infected macaques in comparison to controls
Gene | Name | Fold change | P value |
|---|---|---|---|
FCN1 | Ficolin (collagen/fibrinogen domain containing) 1 | 20.26 | 0.01837 |
APOBEC3A | Apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3A | 15.34 | 0.04385 |
GZMA | Granzyme A | 14.96 | 0.04000 |
MAMU-A | MHC class I antigen | 10.64 | 0.00076 |
GZMB | Granzyme B | 10.02 | 0.00454 |
LPAR5 | lysophosphatidic acid receptor 5 | 9.63 | 0.04561 |
NKG7 | Natural killer cell group 7 sequence | 9.11 | 0.02109 |
PDCD1LG2 | Programmed cell death 1 ligand 2 | 9.11 | 0.02552 |
GPR18 | G protein-coupled receptor 18 | 8.09 | 0.01031 |
LFA2 | Lymphocyte function-associated antigen 2 | 7.74 | 0.00447 |
TIGIT | T cell immunoreceptor with Ig and ITIM domains | 7.53 | 0.04879 |
CHRNA1 | Cholinergic receptor, nicotinic, alpha 1 | 7.28 | 0.04968 |
CLEC2D | C-type lectin domain family 2, member D | 7.01 | 0.03784 |
GLIPR1 | GLI pathogenesis-related 1 | 6.54 | 0.03590 |
BTLA | B- and T-lymphocyte attenuator-like | 6.32 | 0.00352 |